Kelly Brown is one of only two changes to the Scotland 22 that played Ireland last weekend.

The other change sees Scott Gray replace John Barclay to make his first Scotland start since his debut cap.

Scotland coach Frank Hadden said: “Scott has been knocking on the door for some time now and deserves this opportunity, while we’ve gone for Kelly on the bench for the coverage that he provides.

“We’re looking forward to going to Twickenham and seeking back to back Calcutta Cup wins for the first time since 1984.”

Warriors centres Max Evans and Graeme Morrison retain their places in the back-line alongside winger Thom Evans whilst hooker Dougie Hall and prop Moray Low are named amongst the replacements.

Scotland team (sponsor Murray) to play England in the RBS 6 Nations Championship at Twickenham on Saturday 21 March (kick-off 3.30pm)

15 Chris Paterson (Edinburgh)

14 Simon Danielli (Ulster)
13 Max Evans (Glasgow Warriors)
12 Graeme Morrison (Glasgow Warriors)
11 Thom Evans (Glasgow Warriors)

10 Phil Godman (Edinburgh)
9 Mike Blair (Edinburgh) CAPTAIN

1 Alasdair Dickinson (Gloucester)
2 Ross Ford (Edinburgh)
3 Euan Murray (Northampton Saints)
4 Jason White (Sale Sharks)
5 Jim Hamilton (Edinburgh)
6 Alasdair Strokosch (Gloucester)
7 Scott Gray (Northampton Saints)
8 Simon Taylor (Stade Francais)

Substitutes
16 Dougie Hall (Glasgow Warriors)
17 Moray Low (Glasgow Warriors)
18 Nathan Hines (Perpignan)
19 Kelly Brown (Glasgow Warriors)
20 Chris Cusiter (Perpignan)
21 Nick De Luca (Edinburgh)
22 Hugo Southwell (Edinburgh)

Referee: Marius Jonker (South Africa).  Touch-judges: Christophe Berdos (France) and Simon McDowell (Ireland).  TMO: Carlo Damasco (Italy)